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. 2021 Apr 7;11:7614. doi: 10.1038/s41598-021-87289-6

Figure 2.

Figure 2

Performance of antibody tests assessed using samples with defined IgG antibody titers. The IgG titers, ranging from 80 to > 320, were determined using an in-house immunofluorescence assay (IFA). (A) The proportion of samples testing positive in rapid diagnostic IgG tests. The reference set of positive samples included 5 samples with a IgG titer of 80, 21 samples with a titer of 160, 39 samples with a titer of 320, and 22 samples with a IFA titer of > 320. (B) The proportion of samples testing positive in platform-based assays. Epitope, Euroimmun, and in-house RV were evaluated using 220 positive samples and Abbot, Mabtech, and Wantai were evaluated using 104, 217, and 178 positive reference samples, respectively. Among the tested reference samples, 45 tested negative at a dilution of 1:80 (< 80) using IFA, 14 samples had a titer of 80, 39 samples had a titer of 160, 64 samples had a titer of 320, and 58 samples had an IFA titer of > 320.