Table 2.
Specificity and sensitivity of six platform-based SARS-CoV-2 antibody tests.
| Platform-based antibody test | Specificity | Overall sensitivity* | Sensitivity 1–21 days post symptom onset | Sensitivity ≥ 22 days post symptom onset | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | % | 95% CI | N | % | 95% CI | N | % | 95% CI | N | % | 95% CI | |
| Abbott | 115 | 100 | 96.8–100 | 104 | 75.0 | 65.6–83.0 | 32 | 62.5 | 43.7–78.9 | 65 | 81.5 | 70.0–90.1 |
| Epitope | 278 | 68.7 | 62.9–74.1 | 220 | 71.8 | 65.4–77.7 | 72 | 66.7 | 54.6–77.3 | 129 | 75.2 | 66.8–82.4 |
| Euroimmun | 278 | 99.3 | 97.4–99.9 | 220 | 71.8 | 65.4–77.7 | 72 | 44.4 | 32.7–56.6 | 129 | 87.6 | 80.6–92.7 |
| In-house RV | 278 | 99.3 | 97.4–99.9 | 220 | 87.7 | 82.6–91.8 | 72 | 68.1 | 56.0–78.6 | 129 | 99.2 | 95.8–100 |
| Mabtech | 278 | 100 | 98.7–100 | 217 | 79.3 | 73.3–84.5 | 72 | 62.5 | 50.3–73.6 | 126 | 88.1 | 81.1–93.2 |
| Wantai | 260 | 99.6 | 97.9–100 | 178 | 88.8 | 83.2–93.0 | 65 | 78.5 | 66.5–87.7 | 94 | 96.8 | 91.0–99.3 |
CI confidence interval.
*Independent of time between onset of COVID-19 symptoms and sampling.