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. 2021 Mar 25;12:625308. doi: 10.3389/fneur.2021.625308

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Copyright © 2021 Ogier, Hostin, Bellemare and Bendahan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fat fraction map of a thigh of a patient with myotonic dystrophy type 1 (left) and corresponding segmentation of the principal regions of interest (right). Femur is in white. The individual muscles of the knee extensors, knee flexors, and the medial compartment are in red, blue, and green, respectively. Subcutaneous (orange) and perimuscular (purple) tissues are separated by the fascia lata (dot line in dark blue). Patient participated in the randomized controlled trial OPTIMISTIC (5).