Skip to main content
. 2021 Mar 25;12:643089. doi: 10.3389/fphar.2021.643089

FIGURE 4.

FIGURE 4

Skin pathological morphology. Magnification ×40. (A) : H&E staining of the skin;. (B): Masson’s staining of the skin; (C): toluidine blue staining; (D): Dermal thickness of the skin; (E) The number of mast cells. The data were calculated and analyzed using Pad Prism 7.0 (Graph Pad Software, La Jolla, CA, United States) software, group differences were also analyzed by one-way analysis of variance (ANOVA) followed by Duncan’s multiple comparison test. *p < 0.05 compared to the model group; **p < 0.01 compared to model group; ***p < 0.001 compared to the model group. VC: mice treated with vitamin C (300 mg/kg); NMN: mice treated with nicotinamide mononucleotide (300 mg/kg); L: mice treated with L. fermentum TKSN041 (1.0 × 109 CFU/ml); NMN + L: mice treated with nicotinamide mononucleotide (300 mg/kg) and L. fermentum TKSN041 (1.0 × 109 CFU/ml).