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. 2021 Mar 25;12:643089. doi: 10.3389/fphar.2021.643089

FIGURE 5.

FIGURE 5

AMPK, NF-κBp65, IκB-α, SOD1, and CAT mRNA and protein expression levels in skin and liver tissues. (A) AMPK, NF-κBp65, IκB-α, SOD1, and CAT mRNA expression levels in skin and liver tissues; (B) protein stripe chart of AMPK, NF-κBp65, IκB-α, SOD1, and CAT in skin; (C) AMPK, NF-κBp65, IκB-α, SOD1, and CAT protein expression levels in skin. The data were calculated and analyzed using Pad Prism 7.0 (Graph Pad Software, La Jolla, CA, United States) software, group differences were also analyzed by one-way analysis of variance (ANOVA) followed by Duncan’s multiple comparison test. *p < 0.05 compared to the model group; **p < 0.01 compared to model group; ***p < 0.001 compared to the model group. VC: mice treated with vitamin C (300 mg/kg); NMN: mice treated with nicotinamide mononucleotide (300 mg/kg); L: mice treated with L. fermentum TKSN041 (1.0 × 109 CFU/ml); NMN + L: mice treated with nicotinamide mononucleotide (300 mg/kg) and L. fermentum TKSN041 (1.0 × 109 CFU/ml).