TABLE 3.
Skin levels of T-SOD, CAT, IL-10, Na+-K+-ATPase, NAD+, and TNF-α in mice.
| Group | T-SOD (U/mgprot) | CAT (U/mgprot) | Na+K+-ATP (U/mgprot) | NAD+ (nmol/min/mgprot) | TNF-α (ng/L) | IL-10 (pg/ml) |
|---|---|---|---|---|---|---|
| Normal | 26.68 ± 6.52a | 23.07 ± 3.41a | 0.86 ± 0.15a | 16.98 ± 2.49a | 102.18 ± 15.55b | 632.98 ± 82.99a |
| Model | 7.21 ± 1.29d | 15.70 ± 4.20c | 0.22 ± 0.06c | 13.35 ± 0.96c | 154.01 ± 17.99a | 105.40 ± 32.65c |
| VC | 16.44 ± 3.79c | 19.58 ± 2.90b | 0.47 ± 0.15b | 14.89 ± 1.58bc | 145.79 ± 28.39a | 146.99 ± 36.60c |
| NMN | 18.62 ± 3.60c | 21.48 ± 3.99b | 0.60 ± 0.11bc | 15.73 ± 0.84ab | 115.35 ± 9.47b | 259.06 ± 34.66c |
| L | 18.68 ± 1.25c | 21.52 ± 3.43b | 0.62 ± 0.16bc | 14.72 ± 0.42bc | 117.23 ± 17.78b | 223.79 ± 27.68c |
| NMN + L | 25.83 ± 6.06b | 23.80 ± 3.67a | 0.75 ± 0.17a | 16.53 ± 1.03ab | 94.85 ± 14.57b | 376.55 ± 63.75b |
Values are mean ± standard deviation (N = 10/group). The difference in variance between the two groups was significant (p < 0.05).
a-cMean values with different letters in the same column are significantly different (p < 0.05) according to Duncan’s honestly significantly different test. VC: mice treated with vitamin C (300 mg/kg).
NMN, mice treated with nicotinamide mononucleotide (300 mg/kg); L, mice treated with L. fermentum TKSN041 (1.0 × 109 CFU/ml); NMN + L, mice treated with nicotinamide mononucleotide (300 mg/kg) and L. fermentum TKSN041 (1.0 × 109 CFU/ml); T-SOD, total superoxide dismutase; CAT, catalase; TNF-α, tumor necrosis factor α; IL-10, interleukin 10.