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. 2021 Mar 25;11:675442. doi: 10.3389/fonc.2021.675442

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Copyright © 2021 Shen, Zheng, Zhou, Tong, Xu, Gao, Zhang and Fu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Circ_0092314 induces EMT in PAAD cells. (A) Western blotting analysis of the indicated proteins in circ_0092314-silenced or circ_0092314-overexpressing PAAD cells. (B, C) Images of representative invasive PAAD cells are shown (B), and quantification analysis is presented (C). (D) Tumor sphere formation assay for circ_0092314-silenced or circ_0092314-overexpressing PAAD cells, shown by representative images (left) and by quantification (right). (E) qRT-PCR assay of CD133 and CD44 expression in circ_0092314-silenced or circ_0092314-overexpressing PAAD cells. ***P < 0.001.