Fed Akita-PTGOEmice showed an improvement of diabetic symptoms.A, liver glycogen, (B) plasma glucose concentration at 10, 20, and 40 weeks of age, (C) body weight, (D) lean weight, (E) fat weight, (F) food intake per day, (G) water intake per day, and (H) urine volume per day in Akita, Akita-PTGOE, and nondiabetic controls (n = 8–32 in all experiments). Data in A, C–H are from 20-week-old fed animals and are presented in boxplots; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.