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. 2021 Mar 25;9:637248. doi: 10.3389/fcell.2021.637248

FIGURE 2.

FIGURE 2

Effects of umbilical cord blood-derived exosomes on endothelial proliferation, migration, and tube formation. (A) HUVECs were treated with exosomes (50 μg/ml) from NBPD and BPD infants or vehicle for 24 h and 48 h, respectively. Cell proliferation was determined using CCK-8. (B,C) HUVECs were treated as indicated for 16 h, and number of migrated cells was determined by transwell. *,#P < 0.05 versus control and NBPD group, respectively. N = 3. Scale bar = 30 μm. (D,E) HUVECs were treated with exosomes or vehicle as indicated. Tube formation was determined at 6 h after treatments (scale bar = 50 μm). *, # P < 0.05 versus control and NBPD, respectively. n = 3.