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. 2021 Mar 25;9:637248. doi: 10.3389/fcell.2021.637248

FIGURE 6.

FIGURE 6

Effects of hsa-miR-103a-3p, hsa-miR-185-5p, and hsa-miR-200a-3p mimics on endothelial cell proliferation and migration. (A–C) Overexpression of hsa-miR-103a-3p, hsa-miR-185-5p, and hsa-miR-200a-3p in HUVECs. HUVECs were transfected with miRNA mimics for 24 h, and expression of miRNAs was determined by RT-qPCR. (D–F) Cell proliferation was determined at 24 h and 48 h after miRNA mimic transfection. Hsa-miR-103a-3p and hsa-miR-185-5p overexpression promoted endothelial cell proliferation, whereas hsa-miR-200a-3p overexpression suppressed endothelial cell proliferation. (G,H) Cell migration was determined at 6 h after miRNA mimic transfection. Hsa-miR-103a-3p and hsa-miR-185-5p overexpression promoted endothelial cell migration. Hsa-miR-200a-3p overexpression inhibited cell migration. *P < 0.05, versus mimics NC group. n = 3.