Table 1.

Physical and serum parameters of mice between groups.

	Sham (n = 10)	Ovx (n = 10)	Ex (n = 10)	ExRg (n = 10)
Weightpre (g)	20.96 ± 1.89	21.55 ± 2.06	21.21 ± 1.43	21.5 ± 2.55
Weightpost (g)	23.81 ± 2.48	27.99 ± 2.59*	24.13 ± 1.53†	25.29 ± 2.91
Uterus weigh (g)	0.069 ± 0.023	0.020 ± 0.012*	0.030 ± 0.017*	0.025 ± 0.018*
Serum E2 (pg/ml)	8.09 ± 2.47	4.05 ± 1.69*	7.13 ± 1.91†	3.97 ± 1.11*§
Serum irisin (pg/ml)	5.10 ± 1.96	2.04 ± 0.64*	4.34 ± 2.01†	3.05 ± 1.09*
Serum BAP (pg/ml)	0.56 ± 0.10	0.34 ± 0.10*	0.55 ± 0.07†	0.35 ± 0.12*§
Serum TRAP (pg/ml)	4.25 ± 0.61	6.01 ± 1.20*	4.02 ± 1.2†	5.22 ± 0.89*§

Ovx, ovariectomized; Ex, exercise; ExRg, exercise plus cRGDyk; BAP, bone alkaline phosphatase; TRAP, tartrate-resistant acid phosphatase. Data are presented as mean ± SD.

^*Denotes the difference between Sham group and Ovx, Ex, and ExRg groups was significant (p < 0.05);

^† indicates the difference between Ovx group and Ex and ExRg groups was significant (p < 0.05);

^§ presents the difference between Ex group and ExRg group was significant (p < 0.05).