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. 2021 Mar 25;9:655440. doi: 10.3389/fcell.2021.655440

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Copyright © 2021 Yang, Li, Tian, Fu, Gao, Zhao, Cao, Liao, Yuan, Liu and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative macroscopic, radiological and biomechanical properties of repaired tissues at 3 and 6 months postoperation. (A) Representative macroscopy. (B) ICRS scores at 3 and 6 months. (C) Representative 3D and 2D micro-CT images at each time point. Quantitative analysis of (D) BMD and (E) BV/TV (n = 6 knees). The repaired sites were indicated by red circles. (F) Compression modulus of repaired tissues at 3 and 6 months (n = 3 knees). The red circles indicate the repaired areas. Data are means ± SDs (*p < 0.05, ***p < 0.005, ****p < 0.001, n.s. represents no significant difference).