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. 2021 Mar 25;11:647048. doi: 10.3389/fcimb.2021.647048

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Copyright © 2021 Li, Liu, Liu, Sui, Liu, Wei, Liu, Cheng, Ye, Gao, Wang, Lu, Cheng, Zhang, Yuan and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CB RH2 enhances intestinal barrier function of ceftriaxone-treated mice. (A–E) The relative RNA expression of genes encoding zonula occludens (ZO-1), Occludin, Claudin-1, Claudin-4, and mucin-2 (MUC-2) in colon tissues of mice, detected by qPCR; (F, G) Representative blots and comparison of protein expression of ZO-1, Occludin, Claudin-1, Claudin-4, and MUC-2 by western blot with β-actin as internal control. All data were evaluated as mean ± SEM (n = 5), *p < 0.05, **p < 0.01, ****p < 0.0001.