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. 2021 Mar 25;11:647048. doi: 10.3389/fcimb.2021.647048

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Copyright © 2021 Li, Liu, Liu, Sui, Liu, Wei, Liu, Cheng, Ye, Gao, Wang, Lu, Cheng, Zhang, Yuan and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anti-inflammatory effect of CB RH2 on mice with ceftriaxone-induced intestinal dysbacteriosis. (A, B) The relative RNA expression of genes encoding tumor necrosis factor alpha (TNF-α) and cyclooxygenase-2 (COX-2) in colon tissues of mice (n = 5); (C) IL-10 of serum were detected by ELISA following the manufacturer’s protocol (n = 5); (D) Representative flow cytometry plots of CD4⁺ and CD8⁺ T cells identified (n = 3); (E, F) Percentage of CD4⁺ and CD8⁺ T cells in spleen; (G) The proportion of CD4⁺/CD8⁺. All data were evaluated as mean ± SEM, *p <0.05, **p <0.01, ***p <0.001.