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. 2020 Jul 13;42(3):491–498. doi: 10.1038/s41401-020-0456-9

Fig. 2. In vitro autoradiography results of [11C]31 and [11C]37 in rat brain sections.

Fig. 2

a [11C]31 (baseline), pretreatment with 31 (self-blocking, 10 μM), BMT-108908 (10 μM) and (+)-CP101606 (10 μM). b Quantitative analysis of the baseline and blocking experiments (n = 4, see quantitative data in Supporting Information Table). c [11C]37 (baseline), pretreatment with 37 (self-blocking, 10 μM), BMT-108908 (10 μM) and (+)-CP101606 (10 μM). d Quantitative analysis of the baseline and blocking experiments (n = 4, see quantitative data in Supporting Information Table). The value is expressed as the ratio of the radioactivity of different brain regions to that of the cerebellum (reference region). Hi hippocampus, Cx cerebral cortex, St striatum, Th thalamus, Cb cerebellum. Asterisks indicate statistical significance: ****P < 0.0001, ***P < 0.001, **P < 0.01, *P < 0.05, and N.S. = no statistics.