Fig. 1.

Overview figure of parameters and criteria for risk management decision-making. Overview of (theoretically) possible parameters/criteria (red and green boxes read horizontally across) for risk management decision-making with respect to IgE-mediated allergenicity of new or modified food proteins. Risk management decision-making could be based on a single parameter/criterion or on combinations of parameters/criteria. Green: an acceptable situation; red: a non-acceptable situation. Each (theoretically) possible option has specific implications for risk management and the methods and data needed for the assessment. Reprinted from: Defining the targets for the assessment of IgE-mediated allergenicity of new or modified food proteins, vol. number: 127, Houben G. et al., pages no. 61-9, copyright (2019) with permission from Elsevier [11].