Invasive procedure steps. After acquisition of the baseline angiography, pre‐PCI FFR is measured followed by a motorized pullback evaluation. The wire position for the distal FFR measurement is recorded with a contrast injection for off‐line co‐registration with the FFRCT model. Subsequently, OCT is performed to assess lesion characteristics, define stent size and PCI strategy. The position of the stent, before deployment, is recorded with a contrast injection to co‐localize the stent position in the FFRCT model for application of the Planner (dashed white line). Following PCI, OCT is performed to assess final stent expansion and apposition. FFR and motorized pullback evaluation are then repeated. The position of the pressure sensor is recorded with a contrast injection (white star). The procedure is completed with final coronary angiography of the target vessel. FFRCT, fractional flow reserve derived from CT. FFR Fractional flow reserve; OCT, optical coherence tomography