Table 2.
Incidence of EAD, DAD, and TA caused by ACO or MACO with or without TTX or OUA
| DAD | TA | EAD | DAD | TA | ||
|---|---|---|---|---|---|---|
| ACO | 4/7 | 7/7 | MACO | 4/8 | 6/8 | 8/8 |
| ACO+TTX | 0/7* | 0/7** | MACO+TTX | 2/8 | 0/8** | 0/8** |
| ACO+OUA | 1/8 | 5/8 | MACO+OUA | 4/5 | 1/5 | 5/5 |
TTX reduced the incidence of DAD, EAD, or TA caused by ACO or MACO significantly (*P < 0.05, **P < 0.01, respectively). However, OUA had no significant effect on incidence of DAD, EAD, or TA caused by ACO or MACO
The concentrations of ACO, MACO, TTX, and OUA were 3, 0.3, 2, and 0.1 μM, respectively.
EAD early after-depolarization, DAD delayed after-depolarization, TA triggered activities.