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. 2020 Oct 3;15(2):534–544. doi: 10.1038/s41396-020-00794-w

Fig. 2. Relative fitness of bacterial populations with CRISPR-mediated immunity at 3 d.p.i. when competing with a surface mutant.

Fig. 2

Competitions were carried out between a marked surface resistant strain and either the WT PA14 (purple), a mutant PA14 lacking a functional cas1 (orange) or a WT-derived strain carrying two additional spacers targeting phage DMS3mvir (BIM2; green). Experiments were carried out across a gradient of phage titres, as indicated. The phage used (DMS3mvir) is a mutant of DMS3vir that is targeted by WT PA14. n = 8 replicates per genotype per phage titre. a Data presented with phage titre as a continuous variable. b Data grouped by phage titre to better visualise differences within titres.