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. 2020 Nov 2;28(4):1284–1300. doi: 10.1038/s41418-020-00651-5

Fig. 4. Inhibition of MerTK signaling blocks PD-L1-overexpression induced tumour growth in murine model.

Fig. 4

a Representative images of tumours in these four groups. See the Methods for details. b, c Tumour volume and weight in the PD-L1overexpression and control groups with or without UNC2025 treatment. d Western blot assay of p-MerTK, MerTK, p-AKT, AKT, p-Erk, Erk, Bcl-2 and Cyclin D1 protein levels in these four groups. e IHC assay of KI-67 and p-MerTK expression (Scale bar: 100 μm). Data were presented as the mean ± SD. Data were analysed using two-way ANOVA analysis followed by Bonferroni’s post hoc test. ***P < 0.001 vs. control or as indicated.