Table IV.

Influence of various factors including serum IL-37 on the presence of carotid atherosclerotic plaque assessed by univariate analysis and subsequent multivariate linear regression analysis.

		Univariate			Multivariate
Variable	Cut-off value	Adjusted β	95% CI of β	P-value	Adjusted β	95% CI of β	P-value
IL-37	>30.9 mg/ml	0.180	0.078-0.280	0.018	0.110	0.014-0.206	0.024
Hypertension	Yes	0.183	0.081-0.285	<0.001	0.103	0.001-0.205	0.047
Non-dipper	Yes	0.191	0.090-0.293	<0.001	0.123	0.024-0.223	0.016
Age	>55 years	0.216	0.115-0.317	<0.001	0.187	0.088-0.286	<0.001
Sex	Yes	0.024	-0.079-0.126	0.646
Smoking	Yes	0.282	0.183-0.381	<0.001	0.239	0.142-0.336	<0.001
Drinking	Yes	0.003	-0.100-0.107	0.950
Obesity	Yes	0.083	-0.020-0.186	0.115
T2DM	Yes	0.147	0.044-0.249	0.005	0.036	-0.066-0.137	0.491
HLP	Yes	0.124	0.022-0.227	0.018	0.037	-0.060-0.134	0.452
SAHS	Yes	0.185	0.084-0.287	<0.001	0.211	-0.045-0.467	0.106
Hypoxemia	Yes	0.156	0.054-0.258	0.003	-0.084	-0.340-0.173	0.522
CREA	>92 µmol/l	0.039	-0.065-0.142	0.464
CRP	>6.8 mg/l	-0.069	-0.172-0.034	0.191	-0.068	-0.164-0.027	0.160
Hcy	>17.9 µmol/l	0.016	-0.088-0.119	0.767

IL, interleukin; T2DM, type 2 diabetes mellitus; HLP, hyperlipidemia; SAHS, sleep apnea hypopnea syndrome; CREA, creatinine; CRP, C-reactive protein; Hcy, homocysteine.