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Effects of oral administration of AuNPs for 90 days on liver and renal histology in male and female mice. (a) H&E staining shows no histopathological lesion in liver and kidney, except for a slight inflammatory infiltration of the male mice kidney cells (indicated by black arrows) on treatment with high dosage of AuNPs. (b) Sirius red staining of hepatic and renal tissues shows no obvious interstitial fibrosis in male and female mice treatment with AuNPs. Scale bar = 50 μm.
