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. 2020 Jul 21;42(2):189–198. doi: 10.1038/s41401-020-0433-3

Fig. 7. Tonic activation of D2Rs in spinal cord dorsal horn is impaired in the unilateral 6-OHDA-lesioned mice.

Fig. 7

Typical traces of sEPSCs recorded from an SDH neuron of a saline control mouse (a) and from a neuron of a 6-OHDA-lesioned mouse (c). Time course of the sEPSC frequency before, during, and after 6 min of sulpiride (10 µM) in an SDH neuron from a saline control mouse (b) and in an SDH neuron from a 6-OHDA-lesioned mouse (d). e Summarized data showing potentiation of the sEPSC frequency by sulpiride in SDH neurons from the saline control mice and the 6-OHDA-lesioned mice. Saline (n = 15) vs 6-OHDA (n = 13), t = 3.17, P = 0.004, unpaired t-test. f Summarized data showing the changes in the sEPSC amplitude in SDH neurons from the saline control mice and the 6-OHDA-lesioned mice. Saline (n = 15) vs 6-OHDA (n = 15), t = 1.78, P = 0.086, unpaired t-test.