CNO injections induced a significant increase in average wait time during extinction but not during testing selectively in the hM4Di group. The average wait time (IRT), coefficient of variation (CV), expected reward rate (ERR), and percentage of maximum expected reward rate (PMERR) for the conflict option for hM4Di group (A), for the reward only option for hM4Di (B), conflict option for GFP (C), and reward option for GFP virus groups (D) are shown. All data shown as mean values ± SEM.