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. 2021 Apr 8;8(2):025001. doi: 10.1117/1.NPh.8.2.025001

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© 2021 The Authors

Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Fig. 5 — Absolute ${CMRO}_{2}$ values ( $μ M O_{2} / \min$ ) measured with our combined SFDI + LSI optical system are in agreement with absolute ${CMRO}_{2}$ values reported in preclinical studies using different imaging modalities (MRI/MRS, PET). Each LSI + SFDI data point represents an individual subject ( $n = 10$ ) imaged in this report. Each data point for MRI/MRS and PET represents the reported average ${CMRO}_{2}$ of the subjects measured in individual studies.