Table 1.
Clinical characteristics of the patients infected with mild-to-moderate SARS-CoV-2
| Variables | Total (n = 51) | Moderate (n = 31) | Mild (n = 20) | P |
|---|---|---|---|---|
| Ever went to Hubei (n,%) | 0.539 | |||
| Yes | 36 (70.6) | 23 (74.2) | 13 (65.0) | |
| No | 15 (29.4) | 8 (25.8) | 7 (35.0) | |
| Age, years | 34.0 (20.0, 44.0) | 37.0 (25.0, 48.0) | 31.0 (16.0, 37.5) | 0.288 |
| Gender (n,%) | 0.813 | |||
| Male | 24 (47.1) | 15 (48.4) | 9 (45.0) | |
| Female | 27 (52.9) | 16 (51.6) | 11 (55.0) | |
| Incubation time, days | 7.5 (1.0, 11.75) | 8.0 (1.75, 12.0) | 6.5 (0.0, 9.0) | 0.361 |
| Time to negative nucleic acid testing, days | 3 (2, 7) | 2 (4, 8) | 2.5 (1.25, 5.5) | 0.291 |
| Symptoms at admission | ||||
| Fever (n,%) | 34 (66.7) | 23 (74.2) | 11 (55.0) | 0.156 |
| Duration of fever, days | 5.0 (2.0, 7.0) | 5.0 (2.0, 7.5) | 4.0 (2.0, 6.0) | 0.772 |
| Cough (n,%) | 31 (60.8) | 22 (71.0) | 9 (45.0) | 0.083 |
| Expectoration (n,%) | 6 (11.8) | 4 (12.9) | 2 (10.0) | 1.000 |
| Sore throat (n,%) | 6 (11.8) | 3 (9.7) | 3 (15.0) | 0.668 |
| Headache (n,%) | 4 (7.8) | 1 (3.2) | 3 (15.0) | 0.287 |
| Fatigue (n,%) | 2 (3.9) | 2 (6.5) | 0 (0.0) | 0.514 |
| Stuffy and runny nose (n,%) | 4 (7.8) | 1 (3.2) | 3 (15.0) | 0.287 |
| Gastrointestinal reaction (n,%) | 5 (9.8) | 4 (12.9) | 1 (5.0) | 0.636 |
| Chest tightness and dyspnea (n,%) | 7 (13.7) | 5 (16.1) | 2 (10.0) | 0.690 |
| Symptoms after two sequential negative nucleic acid testing | ||||
| Fever (n,%) | 0 (0) | 0 (0) | 0 (0) | – |
| Cough (n,%) | 17 (33.3) | 11 (35.5) | 6 (30.0) | 0.767 |
| Expectoration (n,%) | 7 (13.7) | 5 (16.1) | 2 (10.0) | 0.690 |
| Sore throat (n,%) | 4 (7.8) | 3 (9.7) | 1 (5.0) | 1.000 |
| Headache (n,%) | 2 (3.9) | 0 (0.0) | 2 (10.0) | 0.149 |
| Fatigue (n,%) | 3 (5.9) | 1 (3.2) | 2 (10.0) | 0.553 |
| Stuffy and runny nose (n,%) | 3 (5.9) | 0 (0.0) | 3 (15.0) | 0.055 |
| Gastrointestinal reaction (n,%) | 3 (5.9) | 2 (6.5) | 1 (5.0) | 1.000 |
| Chest tightness and dyspnea (n,%) | 3 (5.9) | 1 (3.2) | 2 (10.0) | 0.553 |
| Pulse oximeter O2 saturation, % | 97.3 ± 0.95 | 97.1 ± 0.89 | 97.6 ± 1.00 | 0.469 |
| Heart rate, breaths/min | 86.7 ± 15.5 | 85.9 ± 15.7 | 88.0 ± 15.5 | 0.938 |
| Disease history | ||||
| Bronchial or pulmonary disease (n,%) | 4 (7.8) | 4 (12.9) | 0 (0.0) | 0.094 |
| Other diseases (n,%)a | 6 (11.8) | 6 (19.6) | 0 (0.0) | 0.036 |
| Treatment (n,%)b | 0.216 | |||
| Western medicine | 17 (34.7) | 11 (35.5) | 6 (33.3) | |
| Chinese medicine | 15 (30.6) | 7 (22.6) | 8 (44.4) | |
| Both | 17 (34.8) | 13 (41.9) | 4 (22.2) | |
Chinese medicine: Jin Hua Qing Gan particles, antiviral particles, Xiang Sha Liu Jun pills, etc.
aOther underlying diseases include glioma, nephrectomy, hyperlipidemia, gastric tumours, type 2 diabetes and thyroid cancer, etc.
bWestern medicine: levofloxacin, moxifloxacin, ribavirin, abidol, lopinavir, ritonavir, interferon, thymoxin, chloroquine phosphate, interferon, oseltamivir, etc.