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. 2021 Mar 23;6(13):9269–9278. doi: 10.1021/acsomega.1c00824

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© 2021 The Authors. Published by American Chemical Society

Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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Relationship between time-dependent change in the Young’s modulus (ΔE) of the HAP/Col hydrogels and the relative DR. (a) Dot plots of each HAP/Col hydrogel for analyzing the correlation between ΔE and relative DR. The plots were fitted by linear regression. (b) Value of the line slope of each HAP/Col hydrogel. The slope values of the 0/3.8, 100/3.8, and 200/3.8 hydrogels were calculated to be 23.86 ± 1.38, 20.92 ± 0.74, and 7.71 ± 0.37, respectively. (c) Schematic illustrated the degradation mechanisms of the HAP/Col hydrogels as the HAP concentration increases.