Table 1.
Case ID (n = 23) | Age | Sex | Status | Cause of death | Disease duration (years) | PMI (hours) | Brain pH | Fixation (months) | CDR | ABC score | AD likelihood b | APOE genotype |
---|---|---|---|---|---|---|---|---|---|---|---|---|
M01 | 69 | Male | Control | Cardiac failure | – | 16 | 6.6 | 97 | – | A3 B1 C3 | Low | E3/E4 |
M02 | 74 | Female | Control | Cancer | – | 20 | 6.59 | 19 | – | A3 B1 C3 | Low | E3/E4 |
M03 | 76 | Female | AD | Cardiorespiratory failure | 11 | 3 | 5.98 | 35 | 3 | A3 B2 C3 | Intermediate | E3/E4 |
M04 | 77 | Male | AD | Aspiration pneumonia | 9 | 26 | 6.34 | 12 | 2 | A3 B3 C2 | High | E4/E4 |
M05 | 78 | Female | Control | Respiratory failure | – | 11 | 6.3 | 78 | – | A0 B0 C0 | Low | E3/E3 |
M06 | 78 | Female | Control | Toxicity | – | 45 | 6.05 | 58 | – | A0 B1 C0 | Low | E3/E4 |
M07 | 81 | Male | Control | Cardiac failure | – | 29 | 6.57 | 26 | – | A0 B2 C0 | Low | E3/E3 |
M08 | 80 | Male | Control | Respiratory failure | – | 12 | 6.5 | 9 | – | A0 B0 C0 | Low | E3/E3 |
M09 | 80 | Female | AD | Alzheimer's disease | 10 | 32 | 6.54 | 25 | 3 | A3 B3 C3 | High | E3/E4 |
M10 | 82 | Female | Control | Respiratory failure | – | 7.5 | 6.45 | 102 | – | A3 B1 C2 | Low | E3/E3 |
M11 | 83 | Male | AD | Cerebrovascular | 5 | 25 | 6.26 | 70 | 3 | A3 B3 C3 | High | E4/E4 |
M12 | 83 | Female | AD | Uraemia | 7 | 3 | 5.88 | 61 | 3 | A3 B3 C2 | High | E3/E4 |
M13 | 84 | Female | AD | Aspiration pneumonia | 13 | 6 | 6.32 | 64 | 3 | A3 B3 C3 | High | E3/E4 |
M14 a | 85 | Male | Control | Cancer | – | 9 | 6.57 | 61 | – | A2 B2 C3 | Intermediate | E3/E3 |
M15 | 85 | Female | Control | Respiratory failure | – | 10 | 6.63 | 34 | – | A2 B1 C0 | Low | E3/E3 |
M16 | 85 | Female | Control | Pneumonia | – | 23 | 6.44 | 73 | 0 | A2 B0 C1 | Low | E3/E3 |
M17 | 85 | Female | AD | Cardiorespiratory failure | 5 | 10 | 5.91 | 15 | 3 | A3 B3 C3 | High | E3/E3 |
M18 a | 87 | Female | Control | Cancer | – | 5 | 6.38 | 34 | – | A2 B2 C0 | Intermediate | E3/E4 |
M19 a | 92 | Female | Control | Pancytopenia | – | 5 | 6.08 | 34 | 0 | A2 B2 C2 | Intermediate | E3/E3 |
M20 | 93 | Female | Control | Cardiac failure | – | 21 | 6.96 | 81 | 0.5 | A1 B0 C0 | Low | E3/E3 |
M21 a | 87 | Female | Control | Acute peritonitis | – | 24 | – | – | 0 | A3 B2 C1 | Intermediate | – |
M22 | 98 | Female | AD | Cerebrovascular | 6 | 11 | 6.11 | 18 | 3 | A3 B3 C2 | High | E3/E3 |
M23 a | 102 | Female | Control | Acute renal failure | – | 5 | 5.92 | 35 | 0 | A2 B2 C2 | Intermediate | E2/E3 |
High‐pathology controls.
As per NIA‐AA diagnostic criteria 35.