Table 2.
Demographic, clinical and pathological characteristics of cohort. a
| Control (n = 15) | AD (n = 8) | P‐value | |
|---|---|---|---|
| Sex (male/female) | 4, 11 | 2, 6 | 0.9 |
| Age (years) | 83.9 ± 8.1 | 83.3 ± 6.8 | 0.9 |
| Disease duration (years) | – | 8.3 ± 3.0 | – |
| ABC score (Low, intermediate, high) | 10, 5, 0 | 0, 1, 7 | <0.0001 |
| Braak stages (0/I/II, III/IV, V/VI) | 11, 4, 0 | 0, 2, 6 | 0.0002 |
| Brain pH | 6.4 ± 0.27 | 6.2 ± 0.24 | 0.03 |
| PMI (hours) | 16.2 ± 11.1 | 14.5 ± 11.5 | 0.8 |
| Fixation (months) | 52.9 ± 29.7 | 37.5 ± 23.9 | 0.2 |
| Brain weight (g) | 1241 ± 150.7 | 1086 ± 163 | 0.04 |
| APOE ε4 (no/yes) | 10, 4 b | 2, 6 | 0.04 |
a
Mean ± standard deviation throughout.
b
APOE genotype of one control case missing (M21).