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. 2018 Jul 5;29(1):28–44. doi: 10.1111/bpa.12617

Figure 6.

Figure 6

A–F. Photomicrographs depicting cellular distribution of PS1 in the hippocampus of saline‐treated control (A, B) and following 12 h (C, D) and 12 day (E, F) kainic acid‐treated rats at lower (A, C, E) and higher (B, D, F) magnifications. Note the expression of PS1 in pyramidal and granule cell layers in control rats, whereas after 12 day kanic acid treatment PS1 is evident mostly in glial cells of the hippocampus. G–J. Double immunofluorescence photomicrographs showing a subset of GFAP‐labeled astrocytes (G, H), but not ED1‐labeled microglia (I, J), exhibit immunoreactive PS1 in 12 day kainic acid‐treated rat. Py, pyramidal cell layer; DG, dentate gyrus. Scale bar, 100 µM.