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. 2018 Feb 21;28(5):631–643. doi: 10.1111/bpa.12586

Figure 1.

Figure 1

Unaltered motor learning but progressive motor phenotype in L7‐Mfp2 −/− mice. A. The increased clinical score of 6‐ and 9‐months‐old L7‐Mfp2−/− mice is mainly determined by the presence of pronounced hind limb clasping. B. Rotarod testing of naive WT and L7‐Mfp2 knockout mice on five consecutive days reveals a similar pattern of motor learning in both groups. C. The accelerating rotarod shows progressive motor deterioration in L7‐Mfp2−/− mice from the age of 12 months. N = 4–8 mice per group. Results are displayed as mean ± SEM. NS: not significant; *P < 0.05; ***P < 0.001.