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. 2018 Feb 21;28(5):631–643. doi: 10.1111/bpa.12586

Figure 2.

Figure 2

Late‐onset cerebellar ataxia in L7‐Mfp2−/− mice. A,B. CatWalk analysis at the age of 6 and 10 months reveals worsening postural changes and gait abnormalities in L7‐Mfp2−/− mice. C,D. Significant increases in the number of paw slips and the time needed to cross on beams with an increasing degree of difficulty (1 and 0.5 cm) indicates that ataxia initiates in 6‐ to 8‐months‐old L7‐Mfp2−/− mice. N = 4–5 mice per group. Results are displayed as mean ± SEM. NS: not significant, *P < 0.05, **P < 0.01, ***P < 0.001.