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. 2017 Jun 12;28(4):495–506. doi: 10.1111/bpa.12533

Figure 5.

Figure 5

Perivascular pSMAD2/3 granules showed a linear alignment in a vessel with a longitudinal cut in HCHWA‐D occipital cortex. Immunohistofluorescent double staining with neuronal (MAP‐2) and astrocytic (GFAP) cytoskeleton markers. A‐B. pSMAD2/3 TSA (green) and nuclei (blue) channels. C‐D. Detail including MAP‐2 (red; C) or GFAP (red; D). Presence of perivascular pSMAD2/3 granules along the neuronal MAP‐2 dendrites (C), and never colocalizing with GFAP processes (D). Consecutive sections of HCHWA‐D H1 patient‐occipital cortex, merged confocal stack. Scale bar (A‐B) 25 μm; (C‐D) 10 μm.