Table 1.
Case list with clinical features.
| Case | Age (Yr)/Sex | Location | Histology | Radiation, dose | Chemotherapy | Local recurrence | Dissemination | Extra CNS metastasis | Clinical outcomes |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 21/M | Temporo‐parietal lobe | E‐GBM with DA | Extended focal, 64.8 Gy | MCNU | NA | Yes | Scalp |
Dead, 7months |
| 28 | 12/F | Temporal lobe | PXA | No | No | Yes | No | No | – |
| (Rec) | 25/F | Temporal lobe | E‐GBM | Extended focal, 60 Gy | TMZ | NA | Yes | No |
Dead, 4.3 months |
| 311 | 26/F | Frontal lobe | E‐GBM with DA | Extended focal, 60 Gy | TMZ | No | Yes | Scalp |
Dead, 2 months |
| 4 | 47/M | Parietal lobe | E‐GBM with AA | NA | NA | NA | NA | NA | NA |
| 59 | 22/M | Occipital lobe | E‐GBM with DA | Extended focal | TMZ+IFN | Yes | Yes | Vertebral bodies, lung thoracic wall, liver |
Alive at 24 months |
| 6 | 32/M | Parietal lobe | E‐GBM with PXA | Extended focal, 67 Gy | TMZ | No | No | No |
Alive at 10 months |
| 710 | 18/M | Temporal lobe | E‐GBM with DA | Whole brain, 40 Gy | TMZ+IFN | Yes | Yes | No |
Dead, 2 months |
| 812 | 30/M |
Temporal lobe, basal ganglia |
E‐GBM with OA | Yes | Yes | NA | NA | NA |
Alive at 9 months |
| 9 | 70/M | Parietal lobe | E‐GBM with DA | Extended focal, 40 Gy | TMZ | Yes | Yes | No |
Dead, 7 months |
| 10 | 23/M | Frontal lobe | E‐GBM with DA | Extended focal | PCZ+ACNU+VCR | Yes | Yes | Scalp |
Dead, 3 months |
| 1117 | 18/M | Temporal lobe | E‐GBM | Extended focal | ACNU+IFN | Yes | Yes | No |
Dead, 0.7 months |
| 12 | 32/F | Occipital lobe | E‐GBM | Extended focal, 60 Gy | TMZ | No | No | No |
Alive at 26 months |
| 13 | 47/M | Parietal lobe | E‐GBM |
1st: Extended focal, 60 Gy 2nd: SRT |
1st: TMZ+IFN, 2nd: IFM+CDDP+VP16 |
Yes | Yes | No |
Dead, 25 months |
| 14 | 65/F | Frontal lobe | E‐GBM | Extended focal, 60 Gy | TMZ | NA | NA | NA | Dead |
Abbreviations: Yr = years; M = male; F = female; Rec = recurrence; E‐GBM = epithelioid glioblastoma; DA = diffuse astrocytoma; PXA = pleomorphic xanthoastrocytoma; AA = anaplastic astrocytoma; OA = oligoastrocytoma; NA = not avilable; MCNU = ranimustine; TMZ = temozolomide; IFN = interferon‐beta; PCZ = procarbazine; ACNU = nimustine; VCR = vincristine; SRT = stereotactic radiotherapy; IFM = ifosfamide; CDDP = cisplatin; VP16 = etoposide.