Table 4.

Comparison between the mutation status and immunohistochemistry

Immunohistochemical staining pattern (% strong positive cells)	Mutational analysis							Summary
	Wild type	Missense mutation	Missense and nonsense mutation	Nucleotide deletion	Nonsense mutation	Changes in intron region	Nucleotide deletion and nonsense mutation	IHC	No mutation	Any mutation	% of mutation
0–9 (n = 102)	88	8		2	1	3		Negative	88	14	14%
10–19 (n = 8)	2	4	1		1
20–29 (n = 5)		5
30–39 (n = 1)		1
40–49 (n = 4)		4
50–59 (n = 9)		9						Positive	3	52	95%
60–69 (n = 6)		5		1
70–79 (n = 9)		7	1				1
80–89 (n = 6)	1	5
90–100 (n = 7)		7
Total (n = 157)	91	55	2	3	2	3	1		91	66

Abbreviations: IHC = immunohistochemistry.