Table 4.

Neuroglial cell‐type abundance in control and chronically demyelinated multiple sclerosis optic nerve.Abbreviations: As = astrocytes; DMA = demyelination lesion type A; DMB = demyelination lesion type B; Mic = microglial cells; NAMSON = normal‐appearing multiple sclerosis optic nerve; NHON = normal human optic nerve; Ol = oligodendrocytes/oligodendrocyte lineage cells; OP = NG2 cells/oligodendrocyte progenitor cells; Seg = segment; TS = transverse section

Tissue/Seg (TS area)	Cellsa	Total	As	Mic	Ol	OP
NHONb (∼9 mm2)	Per mm2	670	205	90	340	35
	SEM	5.2	1.7	1.9	2.0	0.4
	%	100	31	13	51	5
NAMSON (9.5 mm2)	Per mm2	633	260	65	290	18
	SEM	6.9	3.8	0.7	1.9	0.3
	%	100	41	10	46	3
DMA (6.0 mm2)	Per mm2	600	260	65	225	5
	SEM	4.4	4.3	1.1	1.7	0.2
	%	100	43	11	38	<1
DMB (5.5 mm2)	Per mm2	650	335	145	170	0
	SEM	7.3	3.5	2.2	1.5	0
	%	100	52	22	26	0

^aCounts averaged from multiple standard (0.2 mm²) fields and expressed as cells per mm² and as a relative percent of the total neuroglia.

^bData from previous study 28.