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. 2012 Nov 1;23(3):274–284. doi: 10.1111/j.1750-3639.2012.00644.x

Figure 8.

figure

SgIII and CPE accumulation in APPswe/PS1dE9 mice. (A) SgIII distribution in wild‐type (left) and transgenic (right) mice. Strong SgIII accumulation is associated in plaques through hippocampus, neocortex and thalamus of the APPswe/PS1dE9 mouse. In both genotypes, mossy fibers are intensely labeled. (B) Higher magnification of the transgenic hippocampus immunolabeled for SgIII. (C) CPE‐positive accumulations in the APPswe/PS1dE9 cerebellar cortex. Scale bars: A, 250 μm; B and C, 100 μm. Abbreviations: nc = neocortex; cc = corpus callosum; CA = regions of the hippocampus; f = fimbria; hb = habenula; th = thalamus; DG = dentate gyrus; so = stratum oriens; sp = stratum pyramidale; sr = stratum radiatum; slm = stratum lacunosum‐moleculare; ml = molecular layer; gl = granular layer.