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. 2014 May 28;24(6):599–606. doi: 10.1111/bpa.12146

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Each extent of neuronal loss and gliosis of spinocerebellar ataxia type 2 ( SCA 2) in comparison with control. A. Dentate nucleus of control. B. No neuronal loss and gliosis of dentate nucleus in SCA2 (case 2). C. Oculomotor nucleus of control. D. Mild neuronal loss and gliosis of oculomotor nucleus in SCA2 (case 2). E. Hypoglossal nucleus of control. F. Mild neuronal loss and gliosis of hypoglossal nucleus in SCA2 (case 3). G. Substantia nigra of control. H. Moderate neuronal loss and gliosis of substantia nigra in SCA2 (case1). I. Anterior horn of control. J. Moderate neuronal loss and gliosis of anterior horn in SCA2 (case 1). K. Pontine nucleus of control. L. Severe neuronal loss and gliosis of pontine nucleus in SCA2 (case 1). (M) Purkinje cells of control. N. Severe neuronal loss and gliosis of Purkinje cells in SCA2 (case 3). O. Inferior olivary nucleus of control. P. Severe neuronal loss and gliosis of inferior olivary nucleus in SCA2 (case 1). (hematoxylin and eosin; scale bars 100 μm).