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. 2014 Dec 17;25(1):51–62. doi: 10.1111/bpa.12221

Figure 1.

figure

Relationship between congophilic amyloid angiopathy ( CAA ) score and small vessel disease ( SVD ) score in each of the main  ApoE  genotype groups [ A lzheimer's disease ( AD ) and non‐ AD  combined]. A progressive shift in the direction of the relationship can be seen from the highest AD risk ε E 4 homozygous group through the intermediate risk groups toward the low AD risk ε E2/E 3 group. A. ε E4E 3 genotype (Spearman's correlation, rho = 0.06, P = 0.59). B. ε E4E 4 genotype (Spearman’ rho = 0.27, P = 0.12). C. ε E3E 3 genotype (Spearman's rho = −0.15, P = 0.20). D. ε E2E 3 genotype (Spearman's rho = −0.73, P < 0.01).