Relationship between congophilic amyloid angiopathy (
CAA
) score and small vessel disease (
SVD
) score in each of the main
ApoE
genotype groups [
A
lzheimer's disease (
AD
) and non‐
AD
combined]. A progressive shift in the direction of the relationship can be seen from the highest AD risk ε
E
4 homozygous group through the intermediate risk groups toward the low AD risk ε
E2/E
3 group. A. ε
E4E
3 genotype (Spearman's correlation, rho = 0.06, P = 0.59). B. ε
E4E
4 genotype (Spearman’ rho = 0.27, P = 0.12). C. ε
E3E
3 genotype (Spearman's rho = −0.15, P = 0.20). D. ε
E2E
3 genotype (Spearman's rho = −0.73, P < 0.01).