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Neuropathological evaluation of 45 cases with dCJD. A. Histopathological examination throughout the whole brain of the dCJD patients revealed that 29 cases (64%) showed the diffuse synaptic type PrP deposition and 16 cases (36%) showed widespread PrP amyloid plaques. None of the dCJD patients had large confluent vacuoles or perivacuolar PrP deposition. B. Frequency of each sCJD subgroup in European countries 30.
