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. 2012 Aug 28;23(1):73–81. doi: 10.1111/j.1750-3639.2012.00626.x

Table 2.

Assessment of diagnostic potential of dye‐enhanced multimodal confocal imaging. Abbreviations: NP = neuropathology; NPV = negative predictive value; PPV = positive predictive value

Comparisons Sensitivity (%) Specificity (%) PPV (%) NPV (%)
Normal vs. abnormal brain tissue 95 100 100 98
Glial vs. nonglial tumors 83 90 91 80
Grade and type of the tumor: all pathologists 63 46 76 32
NP trained* 88 100 100 86
*P‐value 0.0264 <0.0001 <0.0001 0.0016

Multimodal confocal imaging is compared with haematoxylin and eosin (H&E) diagnosis as a standard of care.

NP is significantly better in grading and subclassifying tumors.