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. 2011 Aug 16;22(1):17–25. doi: 10.1111/j.1750-3639.2011.00507.x

Figure 2.

Figure 2

RRP22 mRNA expression in human gliomas stratified for WHO grade and methylation status. Note that RRP22 mRNA expression is significantly decreased in high‐grade (WHO grade III and IV) as compared with low‐grade (WHO grade II) gliomas (A). Tumors with increased RRP22 5'‐CpG island methylation scores (relative to that of non‐neoplastic brain tissue) had a lower mean RRP22 mRNA expression level (0.8) as compared with tumors with absent or low RRP22 methylation (1.3); however, these expression differences missed the significance threshold (B).