Table 3.
Number of positive vessels for β‐amyloid (Aβ), matrix metalloproteinase (MMP)‐2 or MMP‐9 immunostaining from the total number of vessels of each group, according to cerebral amyloid angiopathy (CAA) severity following the pathological criteria described in the Methods section. Representative Aβ immunohistochemistry of CAA different grades.
| Aβ | MMP‐9 | MMP‐2 | |
|---|---|---|---|
| Positivity within the vessel wall | Cellular positivity within or around the vessel | Cellular positivity (a) with or (b) around the vessel | |
| CAA (n = 6) | |||
| Grade 0 | 0/30 (0%) | 0/30 (0%) | (a) 3/30 (10%) |
| (b) 0/30 (0%) | |||
| Grade 1 | 60/60 (100%) | 0/60 (0%) | (a) 0/60 (0%) |
| (b) 16/60 (26.7%) | |||
| Grade 2 | 60/60 (100%) | 2/60 (3.3%) | (a) 12/60 (20%) |
| (b) 37/60 (61.7%) | |||
| Grade 3 | 10/11 (90.1%) | 0/11 (0%) | (a) 7/11 (63.6%) |
| (b) 11/11 (100%) | |||
| Grade 4 | 12/24 (50%) | 1/24 (4.2%) | (a) 12/24 (50%) |
| (b) 24/24 (100%) | |||
| Controls (n = 6) | 0/30 (0%) | 0/30 (0%) | (a) 6/30 (20%) |
| (b) 0/30 (0%) | |||
| |||
Elements shown in bold indicate that the positive staining is ≥50%.