Table 4.
Severity of of Purkinje cells in lobules III–X of the cerebellar hemisphere of the Huntington's disease patients
Patient | III | IV | V | VI | Cr1 | Cr2 | VIIB | VIIIAA | VIIIB | IX | X |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | + | + | + | + | + | ++ | ++ | ++ | ++ | + | + |
2 | + | + | + | + | + | + | + | + | + | + | + |
3 | ++ | + | + | + | + | + | + | + | + | − | − |
4 | − | − | − | + | + | + | + | + | + | − | − |
5 | + | + | + | + | + | + | ++ | ++ | ++ | ++ | ++ |
6 | + | + | + | + | + | + | ++ | ++ | ++ | ++ | ++ |
7 | + | + | + | + | + | + | + | + | + | + | + |
8 | − | + | + | + | + | + | ++ | + | + | + | + |
− = none discernible; + = obvious loss of Purkinje cells in a given cerebellar lobule or lobular area as compared to control cases. ++ = cerebellar lobule or lobular area devoid or nearly devoid of Purkinje cells.