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. 2015 May 7;26(1):62–74. doi: 10.1111/bpa.12255

Figure 3.

figure

Running reduces the levels of phosphorylated tau protein in the brain of APPswe/PS1ΔE9 mice. A. AT8‐positive cells were detected in control (Tg) and runner (Tg runner) APPswe/PS1ΔE9 mice in the cortex (top panel) and hippocampus (bottom panel). Graph shows the quantification of AT8‐positive cell per area in the cortex (B) and hippocampus (C). D. Images show representative images of the immunodetection of AT8‐positive cells (left panels, arrows) near amyloid plaques identified by Th‐S stain (right panels). E. Quantification of the number of AT8‐positive neurons per plaque. Bars represent mean ± SE (n ≥ 5). *P < 0.05.