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. 2014 Oct 30;25(4):401–408. doi: 10.1111/bpa.12182

Table 3.

Correlations between MMSE decline and pathology scores in PDD and DLB patients in BA9 (prefrontal cortex), BA21, 22 (temporal lobe neocortex with the superior and middle temporal gyrus), BA24 (anterior cingulate cortex) and BA40 (inferior parietal lobe neocortex)

(A) n PSS α‐Synuclein Plaques Tangles
BA9 PDD + DLB 65–68 0.343 0.45 0.053 0.264
PDD 30–32 0.509 0.501 0.303 0.291
DLB 35–37 0.176 0.333 −0.139 0.183
BA21 PDD + DLB 65–69 0.406 0.467 0.231 0.291
PDD 28–32 0.358 0.156 0.359 0.302
DLB 36–37 0.423 0.577 0.127 0.217
BA24 PDD + DLB 64–68 0.227 0.315 0.142 0.139
PDD 32 0.255 0.109 0.255 0.268
DLB 32–36 0.132 0.258 0.129 0.036
BA40 PDD + DLB 65–69 0.389 0.475 0.067 0.283
PDD 29–32 0.441 0.309 0.370 0.186
DLB 36–37 0.273 0.474 −0.105 0.272
(B) n Αβ42 Αβ40 Ratio Aβ42:Aβ40
BA9 PDD + DLB 69 0.385 0.314 0.340
PDD 32 0.407 0.345 0.45
DLB 37 0.373 0.21 0.24
BA21 PDD + DLB 68 0.409 0.088 0.240
PDD 31 0.450 0.126 0.290
DLB 37 0.307 0.099 0.09

(A) Correlation (Rs) of pathology summary scores and individual pathology scores with MMSE decline per year. PSS is the summation of α‐synuclein, plaque and tangle scores.

(B) Correlation (Rs) of Aβ40 and Aβ42 enzyme‐linked immunosorbent assay data with MMSE decline per year.

Values are Rs and those indicated in large bold italics indicate statistically significant correlations (P < 0.05) between that variable and MMSE decline.

Abbreviations: DLB = dementia with Lewy bodies; MMSE = Mini Mental State Examination; PDD = Parkinson's disease dementia; PSS = pathology summation score.