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. Author manuscript; available in PMC: 2021 Apr 8.
Published in final edited form as: BMJ Sex Reprod Health. 2019 Nov 21;46(2):139–146. doi: 10.1136/bmjsrh-2018-200206

Table 2.

The percentage of total users who discontinued their contraceptive method either during clinical trials or everyday use, specifically due to adverse events or worries about possible adverse events. The data on discontinuation from everyday use was measured over a four-year period in the United States.

DISCONTINUATION Discontinuation due to adverse events (%)
Contraceptive Men Women Sample size Publication
Injectable Combination Male Contraceptive 6.25 320 Behre et al 2016
Depo-provera Injection 36.6 12529 Daniels et al 2013
Patch 25.8 5631 Daniels et al 2013
COC 22.71 45021 Daniels et al 2013
COC 6.0 1056 Yaz (2017)
COC 6.7 2837 Yasmin (2017)
COC 4.0 1723 Ortho Tri Cyclen-Lo (2019)
Vaginal Ring 13 2501 NuvaRing® (2017)