Table 4.

BRAF V600E, CD34 and pS6 expression in glioneuronal tumors and clinical features: tumor recurrence and postoperative seizure outcome. Abbreviations: GGs = gangliogliomas; DNTs = dysembryoplastic neuroepithelial tumors

Parameters (positive/negative)	Recurrence (No. of patients)			Postoperative seizure outcome			Diagnosis
	Without	With	P‐valuea	Engel I	Engel II‐IV	P‐valuea	GG	DNT	P‐valuea
BRAF V600E	63/105	0/6	0.088	43/90	17/16	0.040	38/55	23/54	0.137
pS6‐DN	96/72	2/4	0.406	61/72	29/4	<0.001	83/10	12/65	<0.001
CD34	107/60	0/6	0.003	80/53	21/11	0.568	66/27	39/38	0.008
pS6 & CD34	73/38	0/4	0.016	47/39	20/3	0.005	62/7	9/35	<0.001
BRAF V600E & pS6‐DN	47/56	0/4	0.129	27/56	17/4	<0.001	38/10	7/49	<0.001
BRAF V600E & CD34	55/53	0/6	0.028	39/49	14/9	0.157	32/22	22/37	0.020
BRAF V600E & pS6‐DN & CD34	40/37	0/4	0.116	24/38	14/3	0.001	32/7	7/34	<0.001

^aFisher's exact test or Pearson's chi square test.