Table 4.
Molecular characteristics of the cases of ePXA and eGBM. Abbreviations: ND = not done; NI = not interpretable
| Case No. | p53 (IHC) | IDH1 (R132H) (IHC) | ATRX (IHC) | INI1(BAF47) (IHC) | BRG1 (IHC) | BRAF V600E (IHC) | EGFR amplification (FISH) | PTEN deletion (FISH) | ODZ3 deletion (FISH) | H3 K27M (IHC) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Negative | ND | ND | Retained | Retained | Positive | ND | ND | Negative | ND |
| 2 | Positive | ND | ND | Retained | Retained | Negative | Negative | Negative | Negative | ND |
| 3 | Negative | ND | ND | Retained | Retained | Positive | ND | ND | Deletion | ND |
| 4 | Negative | ND | ND | ND | ND | Positive | ND | ND | Negative | ND |
| 5 | Positive | ND | ND | Retained | ND | Positive | Negative | Negative | Deletion | ND |
| 6 | Positive | Negative | Retained | Retained | Retained | Negative | Negative | ND | Deletion | Negative |
| 7 | Positive | Negative | Retained | Retained | Retained | Positive | Negative | Monosomy 10 | Negative | Negative |
| 8 | Negative | Negative | Retained | Retained | Retained | Positive | Negative | ND | Deletion | Negative |
| 9 | Negative | Negative | Retained | Retained | Retained | Negative | Negative | Deletion | Deletion | ND |
| 10 | Positive | Negative | Retained | Retained | ND | Negative | Negative | ND | Deletion | ND |
| 11 | Negative | Negative | ND | Retained | ND | Negative | Negative | ND | Deletion | Negative |
| 12 | Negative | Negative | ND | Retained | ND | Positive | Negative | Negative | Deletion | Negative |
| 13 | Negative | Negative | ND | Retained | ND | Positive | Negative | Negative | ND | Negative |
| 14 | Negative | Negative | ND | Retained | ND | Negative | Negative | Negative | Deletion | Negative |
| 15 | Positive | Negative | Lost | Retained | ND | Negative | Negative | Negative | Negative | Positive |
| 16 | ND | Negative | ND | ND | ND | ND | Negative | ND | NI | ND |